⚖️ COMPARISON

Creatinine: Men vs Women

How do metric values differ between men and women? Explore sex-based differences in health benchmarks.

Men
1 mg/dL
Median (50th percentile)
Difference
-20.0%
At median
Women
0.8 mg/dL
Median (50th percentile)
⚠️ Content Quality Notice: This page has limited data (0/10 data points). Page is set to noindex until expanded.
  • Group A has no percentile data
  • Group B has no percentile data

💡 Key Insight

There is a notable difference in creatinine: Men have 20% higher values compared to Women.

Percentile Comparison

PercentileMenWomenDifference
5th0.7 mg/dL0.5 mg/dL-28.6%
25th0.9 mg/dL0.7 mg/dL-22.2%
50th1 mg/dL0.8 mg/dL-20.0%
75th1.1 mg/dL0.9 mg/dL-18.2%
95th1.3 mg/dL1.1 mg/dL-15.4%
Mean1 mg/dL0.8 mg/dL-20.0%

Visual Comparison

MenWomen
5th
0.7
0.5
25th
0.9
0.7
50th
1
0.8
75th
1.1
0.9
95th
1.3
1.1

🔬 Creatinine & Kidney Function

Creatinine is a waste product from muscle metabolism, filtered by the kidneys. It's used to estimate glomerular filtration rate (eGFR), the primary measure of kidney function. Because creatinine production depends on muscle mass, sex-specific equations are essential for accurate eGFR calculation.

Key Research Findings

  • eGFR below 60 mL/min/1.73m² for 3+ months defines chronic kidney disease
  • Cystatin C is an alternative marker less affected by muscle mass
  • Acute kidney injury shows rapid creatinine rises over hours to days
  • Certain medications and creatine supplements can affect levels
📚 Research Note: The CKD-EPI equation (2021) removed race from eGFR calculations, improving equity while maintaining accuracy.
Sources: NKF, NIH

❓ Frequently Asked Questions

Why is creatinine similar between Men and Women?

Creatinine levels reflect muscle mass and kidney function. Higher values in men are due to greater muscle mass, which is why sex-specific reference ranges are used.

Source: NKF

How should I interpret my creatinine compared to these benchmarks?

Find your appropriate demographic group and percentile range. Being in the 25th-75th percentile (middle 50%) is typical. Percentiles below 5th or above 95th may warrant discussion with a healthcare provider, though clinical context is essential—a single measurement rarely tells the whole story.

Source: Clinical Guidelines

How reliable is this comparison data?

This data comes from the CDC's National Health and Nutrition Examination Survey (NHANES), a continuously conducted survey that uses rigorous sampling methodology to represent the U.S. civilian non-institutionalized population. Sample sizes typically exceed 5,000 per demographic group, with weighted analysis accounting for the complex survey design.

Source: CDC NHANES

What This Comparison Means

Understanding differences in creatinine between men and women is important for:

  • Accurate benchmarking – Compare yourself to the appropriate reference population
  • Clinical interpretation – Healthcare providers use demographic-specific ranges
  • Research understanding – Biological and lifestyle factors influence these differences
  • Personalized health goals – Set realistic targets based on your demographic
⚠️ Important: These are population averages. Individual variation within each group is significant. Always consult healthcare providers for personal health advice.

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